Aritra Bose

I am a Staff Research Scientist in the Healthcare and Life Sciences department in IBM T.J. Watson Research Center, Yorktown Heights, NY. I was previously a visiting scientist at the Broad Institute of MIT and Harvard. I completed my PhD in Computer Science from Purdue University, West Lafayette, IN under the guidance of Petros Drineas.

I work in the intersection of Genomics, Artificial Intelligence, and Quantum Computing. My research revolves around making sense of complex, high dimensional genetic data with three broad goals in mind:

  • Develop utility-scale quantum computing algorithms and discover their implications in multi-omics analyses.

  • Developing scalable computational and statistical tools to tackle the ever-growing size of datasets being generated in the field of genomics and medicine.

  • Develop AI methods for complex traits and find the biological underpinnings of complex diseases.



Selected Publications

2024

Daniel Platt, Aldo Guzmán-Sáenz, Aritra Bose, Subrata Saha, Filippo Utro, Laxmi Parida AI-enabled evaluation of genome-wide association relevance and polygenic risk score prediction in Alzheimer's disease, iScience Iscience 27.3 (2024).

2023

Aritra Bose, Myson Burch, Agniva Chowdhury, Peristera Paschou, Petros Drineas Structure-informed clustering for population stratification in association studies, BMC Bioinformatics 24.1 (2023): 411.

Diego Machado Reyes, Aritra Bose, Ehud Karavani, Laxmi Parida FairPRS: adjusting for admixed populations in polygenic risk scores using invariant risk minimization, Pacific Symposium for Biocomputing (2023)

2022

Agniva Chowdhury, Aritra Bose, Samson Zhou, David Woodruff, Petros Drineas A Fast, Provably Accurate Approximation Algorithm for Sparse Principal Component Analysis Reveals Human Genetic Variation Across the World, RECOMB (2021). (Equal Contribution)

2021

Sanjoy Dey, Aritra Bose, Subrata Saha, Prithwish Chakraborty, Mohamed Ghalwash, Aldo Guzman Saenz, Filipp Ultro, NG Kenney, Jianying Hu, Laxmi Parida, Daby Sow, Filippo Utro, Daniel E. Platt, Laxmi Parida, Impact of Clinical and Genomic Factors on COVID-19 Disease Severity, AMIA (2021). (Equal Contribution)

Aritra Bose, Filippo Utro, Daniel E. Platt, Laxmi Parida, Multiple Loci Selection with Multi-way Epistasis in Coalescence with Recombinations, Algorithms (2021)

Aritra Bose, Daniel E. Platt, Laxmi Parida, Peristera Paschou, Petros Drineas, Integrating linguistics, social structure and geography to model gene flow in India, Molecular Biology and Evolution (2021)

Aritra Bose, Daniel E. Platt, Niina Haiminen, Laxmi Parida, Cumulant-based genotype-phenotype interaction networks in Parkinson's Disease , under review (2021)

2020

Aritra Bose, Myson Burch, Agniva Chowdhury, Peristera Paschou, Petros Drineas CluStrat: a structure informed clustering strategy for population stratification , accepted in RECOMB (2020)

2019

Aritra Bose, Vassilis Kalantzis, Eugenia Kontopoulou, Mai Elkady, Peristera Paschou, Petros Drineas, TeraPCA: a fast and scalable software package to study genetic variation in tera-scale genotypes, Bioinformatics (2019)

2017

Aritra Bose, Daniel E. Platt, Laxmi Parida, Peristera Paschou, Petros Drineas, Dissecting Population Substructure in India via Correlation Optimization of Genetics and Geodemographics, bioRxiv (2017)

George Stamatoyannopoulos, Aritra Bose, Athanassios Teodasiadis, Fotis Tsetsos, Anna Plantiga, Nikoletta Psatha, Nikos Zogas, Evangelia Yannaki, Pierre Zalloua, Kenneth K Kidd, Brian L Browning, John Stamatoyannopoulos, Peristera Paschou, Petros Drineas, Genetics of the Peloponnesean populations and the theory of the extinction of the medieval Peloponnesean Greeks , European Journal of Human Genetics (2017).

Full list of publications on Google Scholar

Research profile on ResearchGate


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